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Dr Abolfazl Akbari - Full CV


akbari.abiums.ac.ir

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Personal Information
Email address akbari.abiums.ac.ir
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Google Scholar URL https://scholar.google.com/citations?user=UhDDTfMAAAAJ&hl=en
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Full name Dr. Abolfazl Akbari
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Professional Information
Department اعضای هیات علمی معاونت تحقیقات و فناوری
Academic degree دکترای ( PhD)
Assistant Professor
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Contact Information
Telephone - Office/Work +982166554790
Fax +982166554790
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Brief CV
Molecular Medicine  (Graduated from Tehran University of Medical Sciences). Faculty Member of Colorectal Research Center, Iran University of Medical Sciences.
Specialty field: Designing research studies on the introduction of combination therapies and the identification of noninvasive molecular biomarkers in the diagnosis, prognosis and treatment of colrectal cancer.
Educational records
# Course University City Country Graduation Date Total mean
1 BS Ferdowsi Mashhad Iran 2006 16/7
2 MSc Tehran University of Medical Sciences Tehran Iran 2009 18/7
3 PhD Tehran University of Medical Sciences Tehran Iran 2014 18
Languages
# Language Translation Skill Dialogue Skill
1 Average Good English
Professional skills
# Title Date of activity
1 Cell culture; drug treatment
2 Tumor implantation in nude mice
3 IHC (immunohistochemistry)
4 DNA extraction and purification RNA extraction
5 Plasmid extraction and purification (miniprep)
6 Plasmid profiling
7 PCR
8 SYBER Green real-time PCR
9 miRNA and lncRNA detection
10 cDNA-RFLP
11 Gel electrophoresis
12 Western blotting
13 Low resolution SSP HLA typing (TBG) INNO-LiPa HPV genotyping (Innogenetic)
14 Circulating Tumor Cells (cancer stem cells, breast, ovarian, prostate, colon ) selection/detection; Adna Test
Research interests
# Title Start date
1 Study of gene expression, signaling pathways and molecular mechanisms in cancers and metabolic diseases.
2 Genetic engineering; for functionally evaluation of onco-gene and tumor suppressor genes/proteins in cancer cell signaling
3 Study of miRNAs and their roles in cancers and metabolic diseases (molecular pathways regulated by miRNAs)
4 Research on anti-cancer drugs, delivery and assays (in vitro and in vivo)
Course taught
# Lesson Title Place & Date of Lecture
1 Food microbiology 2008
2 Genetic counceling 2012-2016
3 Laboratory sciences 2013-2017
4 Medical microbiology 2017
5 Biochemistry of chromatin 2013-2015
6 Genetic (non-coding RNAs) 2018
Workshops contributed
# Workshops & Courses Titles Functional Organization Place Date
1 Real-Time PCR technique to study the expression of microRNAs (miRNAs) National Institute of Genetic Engineering & Biotechnology National Institute of Genetic Engineering & Biotechnology 2016
Research projects
# Project Titles Executers Supportive Organization Place of Execution Project Situation Completion Date
1 Synthesis of Magnesium oxide nanoparticles modified with percussion structure with ability to generate heat under controlled radiofrequency field and its application in treatment of liver cancer in animal and in vitro Shahram Agah Iran University of Medical Sciences Institute of cancer Running 2018
2 The study of cell-free circulating DNA and correlation with the expression of tumor suppressor cancer stem cell marker in patient with colorectal cancer and evaluation of clinical significance as progression and diagnostic biomarkers Abolfazl Akbari Iran University of Medical Sciences Iran University of Medical Sciences Running 2017
3 The examination of the differential expression of serum potential oncogenic and tumor suppressor miRNAs for evaluating clinical significance as possible prognostic and diagnostic biomarkers for colorectal cancer Abolfazl Akbari Iran University of Medical Sciences Running -
4 Evaluation of gene expression pattern of immunologic factores and cancer stem cell markers in peripheral blood cells of colorectal cancer patients Iran University of Medical Sciences Running 2018
5 Evaluation of domestic probiotic Lactobacillus spp. on Wnt signaling pathway in in vitro and colorectal cancer mouse model Abolfazl Akbari Iran University of Medical Sciences Iran University of Medical Sciences Running 2018
6 Examination of expression level of serum long non-coding RNAs (lnc-RNAs) lnc-CCAT1 and lnc-ATB in peripheral blood mononuclear cells in colorectal cancer for evaluating as non-invasive and early detection biomarker Abolfazl Akbari Iran University of Medical Sciences Iran University of Medical Sciences Running 2018
7 Charactrization, function and biological role of homeodomain proteinTGIFLX in cancers, with focusing on colorectal cancer: a systematic review Abolfazl Akbari Iran University of Medical Sciences Iran University of Medical Sciences Running 2017
8 Evaluation of the combined effect of photodynamic therapy using conjugated nanoparticles with Curcumin on gene expression of colorectal cancer stem cell markers (Lrig1, Lgr5, Nanog, Oct4) Abolfazl Akbari Iran University of Medical Sciences Iran University of Medical Sciences Running 2019
9 Combination of photodynamic therapy and radiotherapy with corcumin-nonoparticles as photosensitizer in colorectal cancer cell line HT-29 Abolfazl Akbari, Seyed Mohammad Amini Iran University of Medical Sciences Iran University of Medical Sciences Running 2019
Published books
# Title Author(s) Publisher Publish Date Edition Publication Type
1 Microbiology Abolfazl Akbari, Ebrahim Faghihloo Khosravi 2012 1 Translation
2 Immunology Abolfazl Akbari, Mohammad Mehdi Amiri Khosravi 2010 1 Translation
3 Cellular and molecular biology Abolfazl Akbari, Abbas Bahador, Fatemeh Fard Saneie, Zahra Abdossamadi, Mojtaba Memariani Khosravi 2009 2 Translation
Published articles
# Paper title Writer Magazine title Publish year Publish type Article type
1 In vivo identification of novel TGIF2LX target genes in colorectal adenocarcinoma using the cDNA-AFLP method Gholam RezaMobiniab,ArefehGhafaric,SaeidAmanpour,RoohollahFateh,Mohammad HosseinGhahremani, Abolfazl Akbari Arab Journal of Gastroenterology 2018 Full Text Full Text
2 Evaluation of circulating miR-21 and miR-222 as diagnostic biomarkers for gastric cancer Abstract Abstract
3 Silibinin upregulates E-cadherin expression in MKN-45 human gastric cancer cells Abstract Abstract
4 The Role of MicroRNA Signature as Diagnostic Biomarkers in Different Clinical Stages of Colorectal Cancer Abstract Abstract
5 MicroRNA Expression Levels and Histopathological Features of Colorectal Cancer Abstract Abstract
6 The combined application of human adipose derived stem cells and chondroitinase ABC in treatment of a spinal cord injury model Abstract Abstract
7 Cell separation: Potentials and pitfalls Abstract Abstract
8 Quantification of Plasma Cell-Free Circulating DNA at Different Stages of Colorectal Cancer Abstract Abstract
9 In vitro antitumor activity of patulin on cervical and colorectal cancer cell lines Abstract Abstract
10 Can coenzyme Q10 supplementation effectively reduce human tumour necrosis factor-α and interleukin-6 levels in chronic diseases? Protocol for a systematic review and meta-analysis of randomised controlled trials Full Text Full Text
11 Cancer stem cell’s potential clinical implications Abstract Abstract
12 Homeodomain protein transforming growth factor beta-induced factor 2 like, X-linked function in colon adenocarcinoma cells Abstract Abstract
13 Mutation analysis of connexin 50 gene among Iranian families with autosomal dominant cataracts Abstract Abstract
14 Transcriptional regulation of E-cadherin and oncoprotein E7 by valproic acid in HPV positive cell lines Abstract Abstract
15 Transforming growth factor beta-induced factor 2-linked X (TGIF2LX) regulates two morphogenesis genes, Nir1 and Nir2 in human colorectal Abstract Abstract
16 Staphylococcus aureus enterotoxin B down-regulates the expression of transforming growth factor-beta (TGF-β) signaling transducers in human glioblastoma Abstract Abstract
17 Identification of a De Novo 3bp Deletion in CRYBA1/A3 Gene in Autosomal Dominant Congenital Cataract Abstract Abstract
18 Evaluation of circulating cellular DCLK1 protein, as the most promising colorectal cancer stem cell marker, using immunoassay based metho Abstract Abstract
19 Evaluation of SD-208, a TGF-β-RI kinase inhibitor, as an anticancer agent in retinoblastoma Abstract Abstract
20 Digoxin Inhibits Retinoblastoma through Suppressing a Non-canonical TGFβ Signaling Pathway Abstract Abstract
21 Modulation of transforming growth factor‑β signaling transducers in colon adenocarcinoma cells induced by staphylococcal enterotoxin B Abstract Abstract
22 Down-regulation of miR-135b in colon adenocarcinoma induced by a TGF-β receptor I kinase inhibitor (SD-208) Abstract Abstract
23 Effect of copper sulfate on expression of endogenous L1 retrotransposons in HepG2 cells (hepatocellular carcinoma) Abstract Abstract
24 Multiplex polymerase chain reaction (PCR) assay for simultaneous detection of shiga-like toxin (stx1 and stx2), intimin (eae) and invasive plasmid antigen H (ipaH) genes in diarrheagenic Escherichia coli Abstract Abstract
25 Multiplex polymerase chain reaction (PCR) assay for simultaneous detection of shiga-like toxin (stx1 and stx2), intimin (eae) and invasive plasmid antigen H (ipaH) genes in diarrheagenic Escherichia coli Abstract Abstract
26 Salmonella enteritidis and antibiotic resistance patterns: a study on 1950 children with diarrhea. Abstract Abstract
27 Isolation of enteroinvasive Escherichia coli (EIEC) from diarrhea in children by polymerase chain reaction (PCR) technique Abstract Abstract
References
# Persons Contact Information
1 Dr Shahram Agah 66554790
2 Dr Mohsen Masoodi 66554790
3 Dr Mansour Heidari 09122979340
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